Anti-Influenza agent 4

Research use only, not for human use.

Anti-Influenza agent 4 is a potent and selective inhibitor of the influenza virus, effectively inhibiting the A/Parma and A/Roma strains with EC50s of 62 nM and 150 nM, respectively.

Anti-Influenza agent 4 is a potent and selective influenza virus inhibitor with EC50s of 150 nM and 62 nM for strains A/Roma and A/Parma, respectively.

Anti-Influenza agent 4 (compound 5) (0-500 μM; 24 and 48 h) exhibits low cytotoxicity in MDCK cells.Anti-Influenza agent 4 shows highly antiviral activity against influenza strain A/Roma and A/Parma with EC50s of 150±0.07 nM and 62±0.02 nM, respectively.Anti-Influenza agent 4 shows IC50s of 244 nM and 230.7 nM against influenza strain A/Roma and A/Parma in hemolysis inhibition assay.Cell Cytotoxicity Assay Cell Line:MDCK cells Concentration:0-500 μM Incubation Time:24 and 48 h Result:Exhibited low cytotoxicity with a CC50 value of 450 μM.

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Microbiology/Virology

Influenza Virus

Influenza Virus

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522625-85-0

386.42

C19H18N2O5S

>98% (HPLC)

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S(NCC1=CC=CO1)(=O)(=O)C2=CC(NC(=O)C3=CC=C(OC)C=C3)=CC=C2

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(-20℃)

With Ice Pack

≥ 2 years